The antibacterial activity of Artemisia quettensis essential oil and its synergy with imipenem

Background: The widespread use of antibiotics is a cause of mutation in microorganisms and leads to the emergence of new micro organisms and resistance to common antibiotics. The purpose of this study is to investigate the synergistic effect of antibacterial synthetic essential oils of Artemisia quettensis and imipenem antibiotic on Pseudomonas aeruginosa isolated from clinical specimens and comparing it with conventional antibiotics.

Methods: In this in vitro study, Artemisia quettensis.podlech oil was used alone and combined used with standard antibiotics to evaluate their antimicrobial activities. The disk diffusion method was employed.

Results: The essential oil of the plants with antibiotics led to a synergistic effect in some cases, because of injecting a quarter of antibiotics inhibit the growth of bacteria and prevents the creation of the colony.

Conclusion: The combination of essential oils of the Artemisia quettensis with antibiotics may be useful in the fight against emerging microbial drug resistance.