The role of gamma oscillations in central nervous system diseases: Mechanism and treatment

Guan, Ao and Wang, Shaoshuang and Huang, Ailing and Qiu, Chenyue and Li, Yansong and Li, Xuying and Wang, Jinfei and Wang, Qiang and Deng, Bin (2022) The role of gamma oscillations in central nervous system diseases: Mechanism and treatment. Frontiers in Cellular Neuroscience, 16. ISSN 1662-5102

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Abstract

Gamma oscillation is the synchronization with a frequency of 30–90 Hz of neural oscillations, which are rhythmic electric processes of neuron groups in the brain. The inhibitory interneuron network is necessary for the production of gamma oscillations, but certain disruptions such as brain inflammation, oxidative stress, and metabolic imbalances can cause this network to malfunction. Gamma oscillations specifically control the connectivity between different brain regions, which is crucial for perception, movement, memory, and emotion. Studies have linked abnormal gamma oscillations to conditions of the central nervous system, including Alzheimer’s disease, Parkinson’s disease, and schizophrenia. Evidence suggests that gamma entrainment using sensory stimuli (GENUS) provides significant neuroprotection. This review discusses the function of gamma oscillations in advanced brain activities from both a physiological and pathological standpoint, and it emphasizes gamma entrainment as a potential therapeutic approach for a range of neuropsychiatric diseases.

Item Type: Article
Subjects: AP Academic Press > Medical Science
Depositing User: Unnamed user with email support@apacademicpress.com
Date Deposited: 29 Mar 2023 05:55
Last Modified: 02 Sep 2024 12:05
URI: http://info.openarchivespress.com/id/eprint/835

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