Bello-Arroyo, Elísabet and Roque, Hélio and Marcos, Alberto and Orihuel, Javier and Higuera-Matas, Alejandro and Desco, Manuel and Caiolfa, Valeria R. and Ambrosio, Emilio and Lara-Pezzi, Enrique and Gómez-Gaviro, María Victoria (2018) MouBeAT: A New and Open Toolbox for Guided Analysis of Behavioral Tests in Mice. Frontiers in Behavioral Neuroscience, 12. ISSN 1662-5153
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Abstract
Animal behavioral tests are essential to understand the bases of neurologic and psychological disorders, which can be evaluated by different methodological and experimental models. However, the quantification of behavioral tests results is limited by the considerable amount of time needed for manual evaluation and the high costs of automated analysis software. To overcome these limitations, we describe here a new, open source toolbox for ImageJ, called Mouse Behavioral Analysis Toolbox (MouBeAT), designed to analyze different behavioral tests in rodents semi-automatically. These tests include Open Field (OF), Elevated Plus Maze (EPM), Y-maze (YM) test and Morris Water Maze (MWM). MouBeAT showed a high correlation with manual evaluation in all the parameters analyzed for all the behavioral tests, reinforcing its value as an accurate analysis tool. This new tool is freely available online.
Item Type: | Article |
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Subjects: | AP Academic Press > Biological Science |
Depositing User: | Unnamed user with email support@apacademicpress.com |
Date Deposited: | 14 Feb 2023 09:13 |
Last Modified: | 24 Aug 2024 12:27 |
URI: | http://info.openarchivespress.com/id/eprint/484 |