Ala, Alireza and Ghobadi, Jafar and Yaghubi, Haleh and Adib, Ali (2022) The prognostic values of platelet to lymphocyte ratio for predicting mortality in patients with acute mesenteric ischemia: a cross-sectional study. Journal of Research in Clinical Medicine, 10. p. 29. ISSN 2717-0616
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Abstract
Introduction: Acute mesenteric ischemia (AMI) is a life-threatening disease that can cause multi-organ damage and ultimately lead to death. Early diagnosis and treatment significantly reduce morbidity and mortality rates in high-risk patients. This study aimed to explore the prognostic values of platelet to lymphocyte ratio (PLR) in predicting mortality in patients with mesenteric ischemia.
Methods: This prospective study included 126 patients with a complaint of acute abdominal pain, suggesting mesenteric ischemia. Demographic data and measured variables were determined using a pre-designed questionnaire. Statistical analysis was conducted using t test analysis, Spearman correlation analysis, and receiver operating characteristic (ROC) curve.
Results: Of 126 studied cases, mesenteric ischemia was confirmed in 47 patients. The mean age in patients with mesenteric ischemia (68 years) was significantly higher than that of non-ischemic patients (65 years). Mean blood bicarbonate level in non-ischemic patients (13.53 mmol/L) was higher than ischemic patients (11.15 mmol/L) (P<0.0001). PLR in patients with mesenteric ischemia and non-ischemic patients was 159 and 151, respectively; this difference was not statistically significant (P=0.14). The overall mortality rate in this study was 61%.
Conclusion: Even though the PLR increases in patients with systemic inflammation, it cannot distinguish between patients with mesenteric ischemia and other inflammatory conditions.
Item Type: | Article |
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Subjects: | AP Academic Press > Medical Science |
Depositing User: | Unnamed user with email support@apacademicpress.com |
Date Deposited: | 18 Jan 2023 12:17 |
Last Modified: | 25 May 2024 08:41 |
URI: | http://info.openarchivespress.com/id/eprint/224 |