GOSWAMI, H. K. GOSWAMI and CHANG, S. I. (2001) MARKER DOTS ARE EXPELLED BY ATTENUATION IN HETEROCHROMATIN OF A CHROMATID. BIONATURE, 21 (1). pp. 41-48.
Full text not available from this repository.Abstract
Marker dots (1.0-2.5 µ) have been known to emanate from some chromosomes indicating precursors/indicators to chromosomal mutagenesis among certain persons including cancer patients. These are principally euchromatic (GC rich) as evidenced by various banding schedules. This study apart of chromosomal survey has been based on reinvestigation of 110 individuals (out of 605) yielding more than 15000 metaphases for analysis. Marker dots' preferred loci of origin are telomeres and the fundamental mechanism may involve the release of transposable euchromatin by heterochromatic attenuation. Probably this is a precursory mechanism for progressive heterochromatinisation.
Item Type: | Article |
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Subjects: | AP Academic Press > Biological Science |
Depositing User: | Unnamed user with email support@apacademicpress.com |
Date Deposited: | 25 Jul 2024 07:38 |
Last Modified: | 25 Jul 2024 07:38 |
URI: | http://info.openarchivespress.com/id/eprint/1905 |