Antimicrobial Activity of Oxygen Active Gel against Porphyromonas gingivalis Contamination at the Implant-abutment Interface

Background: Bacterial contamination at the dental implant abutment interface through microgap may lead to peri-implant tissue infections resulting to marginal bone loss and affecting the long term success of implants.

Aims: The purpose of this In vitro study in vitro was to evaluate the antimicrobial activity of oxygen active gel (BlueM®) against Porphyromonas gingivalis (Pg) at the implant-abutment interface (IAI) in three different types of implant-prosthetic connections.

Methodology: A total of 45 dental implants with three different types of connections were divided into three groups (n=15/each) according to filling product at the interface: Control (C) - unfilled, BlueM (BM) - oxygen active gel, Chlorexidine (CX) - 2% chlorhexidine gel. They were incubated with a solution containing Pg for 5 days under an aerobic condition. Bacterial contamination at the interface were detected and quantificated by qPCR.

Results: All 45 implants showed contamination at the IAI by Pg after 5 days of incubation, independent of prosthetic connection type. EH type connections showed greater contamination by Pg compared to MT type connections (p=0.0098). No differences were observed among different types of connections in BM and CX groups.

Conclusion: The application of active oxygen gel promoted a reduction in P. gingivalis contamination in EH type connections at the IAI in vitro, but did not eliminate it completely.