Comparing the effects of home-based exercise rehabilitation and center based Cardiac rehabilitation on Liver Enzymes of the patients with coronary Artery disease

Moosavi-Sohroforouzani, Azam and Esfarjani, Fahimeh and Zeynali, Farzaneh (2019) Comparing the effects of home-based exercise rehabilitation and center based Cardiac rehabilitation on Liver Enzymes of the patients with coronary Artery disease. Medical Journal of Tabriz University of Medical Sciences and Health Services, 41 (5). pp. 106-114. ISSN 1608-5671

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Abstract

Background: Liver enzymes are known markers for liver dysfunction which can be associated with the risk of heart disease. This study aimed to compare the effects of the home-based exercise rehabilitation and center-based CR on changes in liver enzymes of patients with heart failure.

Methods: In a semi-experimental study, 40 patients (mean age, 59 ± 6.28 years) voluntarily were divided into 3 groups: home-based exercise rehabilitation (n=13), centre –based CR (n=15) and control (n=12). Liver enzymes (Aspartat aminotransferaz (AST), Alanine aminotransferase (ALT, alkaline phosphatase (ALP), Lactate dehydrogenase (LDH) and Creatine phosphokinase (CPK)) were measured at baseline and after 2 months of CR. Data were analyzed using analysis of covariance (ANCOVA) in P < 0.05 level.

Results: For the centre –based CR group, the levels of LDH and CPK after 2 months were reduced (P<0/05), While there were no significant differences in AST, ALT and ALP levels. Levels of ALT significantly reduce in the home-based exercise rehabilitation group.

Conclusion: CR may have been reduce some of the liver enzymes through increased cardiac output and insulin sensitivity and improved perfusion.

Item Type: Article
Subjects: AP Academic Press > Medical Science
Depositing User: Unnamed user with email support@apacademicpress.com
Date Deposited: 16 Jun 2023 06:00
Last Modified: 20 Jul 2024 09:19
URI: http://info.openarchivespress.com/id/eprint/1542

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